BDBM50064011 7-Butyl-azepan-(2Z)-ylideneamine; hydrochloride::CHEMBL543514::CHEMBL89288

SMILES CCCCC1CCCCC(N)=N1

InChI Key InChIKey=LXZWIIJORJEBKG-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50064011   

TargetNitric oxide synthase, brain(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50064011(CHEMBL543514 | CHEMBL89288 | 7-Butyl-azepan-(2Z)-y...)
Affinity DataIC50: 850nMAssay Description:Inhibitory activity against Neuronal nitric oxide synthase at 100 uM concentration was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50064011(CHEMBL543514 | CHEMBL89288 | 7-Butyl-azepan-(2Z)-y...)
Affinity DataIC50: 1.03E+5nMAssay Description:Inhibition of endothelial nitric oxide synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50064011(CHEMBL543514 | CHEMBL89288 | 7-Butyl-azepan-(2Z)-y...)
Affinity DataIC50: 517nMAssay Description:Inhibition of inducible nitric oxide synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50064011(CHEMBL543514 | CHEMBL89288 | 7-Butyl-azepan-(2Z)-y...)
Affinity DataIC50: 850nMAssay Description:Inhibitory activity evaluated from soluble cell extract of human nNeuronal nitric oxide synthase and partially purified by DEAE-sepharose chromatogra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50064011(CHEMBL543514 | CHEMBL89288 | 7-Butyl-azepan-(2Z)-y...)
Affinity DataIC50: 500nMAssay Description:Inhibitory activity evaluated for soluble cell extract of human Inducible nitric oxide synthase and partially purified by DEAE-sepharose chromatograp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50064011(CHEMBL543514 | CHEMBL89288 | 7-Butyl-azepan-(2Z)-y...)
Affinity DataIC50: 1.03E+5nMAssay Description:Inhibitory activity evaluated from soluble cell extract of human endothelia constitutive enzyme (Endothelial nitric oxide synthase) and partially pur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50064011(CHEMBL543514 | CHEMBL89288 | 7-Butyl-azepan-(2Z)-y...)
Affinity DataIC50: 1.60E+3nMAssay Description:The ability of compound to inhibit mouse Inducible nitric oxide synthase in LPS stimulated mouse RAW cells was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed