BDBM50064076 6-bromo-4-oxo-N-(phenylsulfonyl)-2-(4-(quinolin-2-ylmethoxy)phenyl)-4H-chromene-8-carboxamide::CHEMBL285994::N-{6-Bromo-4-oxo-2-[4-(quinolin-2-ylmethoxy)-phenyl]-4H-chromene-8-carbonyl}-benzenesulfonamide

SMILES Brc1cc(C(=O)NS(=O)(=O)c2ccccc2)c2oc(cc(=O)c2c1)-c1ccc(OCc2ccc3ccccc3n2)cc1

InChI Key InChIKey=KYKXFOAWVGPIOD-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50064076   

TargetCysteinyl leukotriene receptor 1(Guinea pig)
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50064076(6-bromo-4-oxo-N-(phenylsulfonyl)-2-(4-(quinolin-2-...)
Affinity DataKd:  382nMAssay Description:In vitro affinity for CysLT1 receptors on guinea pig lung membranes, measured by displacement of [3H]LTD4.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50064076(6-bromo-4-oxo-N-(phenylsulfonyl)-2-(4-(quinolin-2-...)
Affinity DataIC50: 382nMAssay Description:Antagonist activity at CysLT1 receptor in human dU937 cells assessed as inhibition of LTD4-induced increase of calcium level treated 30 mins before L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed