BDBM50064104 (S)-2-[(S)-5-(2-Fluoro-phenyl)-2-(phosphonomethyl-amino)-pent-4-ynoylamino]-3-methyl-butyric acid::CHEMBL36382

SMILES CC(C)[C@H](NC(=O)[C@H](CC#Cc1ccccc1F)NCP(O)(O)=O)C(O)=O

InChI Key InChIKey=CQXKBNCQQAXWQI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50064104   

TargetEndothelin-converting enzyme 1(Human)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50064104((S)-2-[(S)-5-(2-Fluoro-phenyl)-2-(phosphonomethyl-...)
Affinity DataIC50: 110nMAssay Description:Inhibitory activity was assessed on CHO cells expressing recombinant human Endothelin-converting enzyme 1 (ECE-1).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetNeprilysin(Human)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50064104((S)-2-[(S)-5-(2-Fluoro-phenyl)-2-(phosphonomethyl-...)
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibitory activity against neutral endopeptidase (NEP).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed