BDBM50064107 CHEMBL287971::{[(S)-4-(2,4-Difluoro-phenyl)-1-(3-methyl-butylcarbamoyl)-but-3-ynylamino]-methyl}-phosphonic acid

SMILES CC(C)CCNC(=O)[C@H](CC#Cc1ccc(F)cc1F)NCP(O)(O)=O

InChI Key InChIKey=PHUXKOLFTVYGOR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50064107   

TargetEndothelin-converting enzyme 1(Human)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50064107({[(S)-4-(2,4-Difluoro-phenyl)-1-(3-methyl-butylcar...)
Affinity DataIC50: 140nMAssay Description:Inhibitory activity was assessed on CHO cells expressing recombinant human Endothelin-converting enzyme 1 (ECE-1).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetNeprilysin(Human)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50064107({[(S)-4-(2,4-Difluoro-phenyl)-1-(3-methyl-butylcar...)
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibitory activity against neutral endopeptidase (NEP).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed