BDBM50064126 ({(S)-4-(2,4-Difluoro-phenyl)-1-[2-(3,4-dimethoxy-phenyl)-ethylcarbamoyl]-but-3-ynylamino}-methyl)-phosphonic acid::CHEMBL290287

SMILES COc1ccc(CCNC(=O)[C@H](CC#Cc2ccc(F)cc2F)NCP(O)(O)=O)cc1OC

InChI Key InChIKey=XVKUEQXMAPGNSH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50064126   

TargetEndothelin-converting enzyme 1(Human)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50064126(({(S)-4-(2,4-Difluoro-phenyl)-1-[2-(3,4-dimethoxy-...)
Affinity DataIC50: 160nMAssay Description:Inhibitory activity was assessed on CHO cells expressing recombinant human Endothelin-converting enzyme 1 (ECE-1).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed