BDBM50064127 (S)-5-(2-Fluoro-phenyl)-2-(phosphonomethyl-amino)-pent-4-ynoic acid::CHEMBL448098

SMILES OC(=O)[C@H](CC#Cc1ccccc1F)NCP(O)(O)=O

InChI Key InChIKey=PFOHNQZTJDQTGP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50064127   

TargetEndothelin-converting enzyme 1(Human)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50064127((S)-5-(2-Fluoro-phenyl)-2-(phosphonomethyl-amino)-...)
Affinity DataIC50: 240nMAssay Description:Inhibitory activity was assessed on CHO cells expressing recombinant human Endothelin-converting enzyme 1 (ECE-1).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetNeprilysin(Human)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50064127((S)-5-(2-Fluoro-phenyl)-2-(phosphonomethyl-amino)-...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibitory activity against neutral endopeptidase (NEP).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed