BDBM50064131 CHEMBL289638::{[(S)-4-(2,4-Difluoro-phenyl)-1-phenethylcarbamoyl-but-3-ynylamino]-methyl}-phosphonic acid

SMILES OP(O)(=O)CN[C@@H](CC#Cc1ccc(F)cc1F)C(=O)NCCc1ccccc1

InChI Key InChIKey=FJKQVAPDGNHWQV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50064131   

TargetEndothelin-converting enzyme 1(Human)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50064131({[(S)-4-(2,4-Difluoro-phenyl)-1-phenethylcarbamoyl...)
Affinity DataIC50: 110nMAssay Description:Inhibitory activity was assessed on CHO cells expressing recombinant human Endothelin-converting enzyme 1 (ECE-1).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetNeprilysin(Human)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50064131({[(S)-4-(2,4-Difluoro-phenyl)-1-phenethylcarbamoyl...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibitory activity against neutral endopeptidase (NEP).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed