BDBM50064557 CHEMBL59878::[3-(4-Benzo[d]isothiazol-3-yl-piperazin-1-ylmethyl)-phenyl]-piperidin-1-yl-methanone

SMILES O=C(N1CCCCC1)c1cccc(CN2CCN(CC2)c2nsc3ccccc23)c1

InChI Key InChIKey=NBQHGNXQTOFSDN-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50064557   

Target5-hydroxytryptamine receptor 1A(Rat)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50064557([3-(4-Benzo[d]isothiazol-3-yl-piperazin-1-ylmethyl...)
Affinity DataKi:  2.5nMAssay Description:Compound was evaluated for its binding affinity with 5-hydroxytryptamine 1A receptor using membranes prepared from rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50064557([3-(4-Benzo[d]isothiazol-3-yl-piperazin-1-ylmethyl...)
Affinity DataKi:  41nMAssay Description:Compound was evaluated for its binding affinity with Dopamine receptor D2 using membranes prepared from rat striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed