BDBM50064593 3-{(4R,5S,6S,7R)-4,7-Dibenzyl-5,6-dihydroxy-2-oxo-3-[3-(2H-pyrazol-3-yl)-benzyl]-[1,3]diazepan-1-ylmethyl}-N-(2-morpholin-4-yl-ethyl)-benzamide::CHEMBL304713

SMILES O[C@@H]1[C@@H](O)[C@@H](Cc2ccccc2)N(Cc2cccc(c2)-c2cc[nH]n2)C(=O)N(Cc2cccc(c2)C(=O)NCCN2CCOCC2)[C@@H]1Cc1ccccc1

InChI Key InChIKey=IOMNHKSPZZFZEP-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50064593   

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50064593(3-{(4R,5S,6S,7R)-4,7-Dibenzyl-5,6-dihydroxy-2-oxo-...)
Affinity DataKi:  0.0520nMAssay Description:Inhibition of HIV protease, measured by assaying the cleavage of a fluorescent peptide substrate using HPLCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed