BDBM50065112 CHEMBL81269::N-[4-(5H,11H-Benzo[e]pyrrolo[1,2-a][1,4]diazepine-10-carbonyl)-2-methoxy-phenyl]-2,4-dichloro-benzamide

SMILES COc1cc(ccc1NC(=O)c1ccc(Cl)cc1Cl)C(=O)N1Cc2cccn2Cc2ccccc12

InChI Key InChIKey=JYFKCAWQGRAERG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50065112   

TargetVasopressin V1a receptor(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50065112(N-[4-(5H,11H-Benzo[e]pyrrolo[1,2-a][1,4]diazepine-...)
Affinity DataIC50: 32nMAssay Description:Displacement of [3H]AVP from vasopressin receptor (V1a) from human platelet membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVasopressin V2 receptor(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50065112(N-[4-(5H,11H-Benzo[e]pyrrolo[1,2-a][1,4]diazepine-...)
Affinity DataIC50: 1.90nMAssay Description:Displacement of [3H]AVP from human V2 receptor expressed in murine fibroblast cell line (LV2) membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed