BDBM50065171 (S)-N-((S)-1-Carboxy-2-cyclohexyl-ethyl)-3-{2-[ethyl-(4-piperidin-4-yl-butyryl)-amino]-acetylamino}-succinamic acid::CHEMBL82264

SMILES CCN(CC(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC1CCCCC1)C(O)=O)C(=O)CCCC1CCNCC1

InChI Key InChIKey=RCNHPBQFWAPIOX-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50065171   

TargetIntegrin alpha-IIb/beta-3(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50065171((S)-N-((S)-1-Carboxy-2-cyclohexyl-ethyl)-3-{2-[eth...)
Affinity DataIC50: 17nMAssay Description:Inhibition of radiolabeled fibrinogen binding to activated human platelets.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50065171((S)-N-((S)-1-Carboxy-2-cyclohexyl-ethyl)-3-{2-[eth...)
Affinity DataIC50: 26nMAssay Description:Ability to inhibit the aggregation of fixed human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50065171((S)-N-((S)-1-Carboxy-2-cyclohexyl-ethyl)-3-{2-[eth...)
Affinity DataIC50: 1.01E+6nMAssay Description:Inhibition of HUVEC adhesion to fibrinogen-coated platesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50065171((S)-N-((S)-1-Carboxy-2-cyclohexyl-ethyl)-3-{2-[eth...)
Affinity DataIC50: 1.65E+6nMAssay Description:Inhibition of HUVEC adhesion to fibrinogen-coated platesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50065171((S)-N-((S)-1-Carboxy-2-cyclohexyl-ethyl)-3-{2-[eth...)
Affinity DataIC50: 1.75E+6nMAssay Description:Inhibition of HUVEC adhesion to fibrinogen-coated platesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed