BDBM50065242 6-Benzyloxy-3-isothiocyanato-4-methoxymethyl-9H-beta-carboline::CHEMBL83464

SMILES COCc1c(N=C=S)[nH]cc2nc3ccc(OCc4ccccc4)cc3c12

InChI Key InChIKey=KJUPZRXGDNYFQT-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50065242   

TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
University of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50065242(6-Benzyloxy-3-isothiocyanato-4-methoxymethyl-9H-be...)
Affinity DataKi:  25nMAssay Description:Binding affinity measured using LtK- cell membranes expressing GABA alpha-1-beta-3-gamma-2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Human)
University of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50065242(6-Benzyloxy-3-isothiocyanato-4-methoxymethyl-9H-be...)
Affinity DataKi:  59nMAssay Description:Binding affinity measured using LtK- cell membranes expressing GABA alpha-3-beta-3-gamma-2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGABA-A receptor; alpha-2/beta-3/gamma-2(Human)
University of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50065242(6-Benzyloxy-3-isothiocyanato-4-methoxymethyl-9H-be...)
Affinity DataKi:  82.6nMAssay Description:Binding affinity measured using LtK- cell membranes expressing GABA alpha-2-beta-3-gamma-2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
University of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50065242(6-Benzyloxy-3-isothiocyanato-4-methoxymethyl-9H-be...)
Affinity DataKi:  159nMAssay Description:Binding affinity measured using LtK- cell membranes expressing Gamma-aminobutyric acid A receptor alpha-5-beta-3-gamma-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-3/gamma-2(Human)
University of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50065242(6-Benzyloxy-3-isothiocyanato-4-methoxymethyl-9H-be...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity measured using LtK- cell membranes expressing Gamma-aminobutyric acid A receptor alpha-6-beta-3-gamma-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed