BDBM50065792 (E)-3-(3,4-Dimethoxy-phenyl)-acrylic acid 2-methyl-quinolin-8-yl ester::CHEMBL432775

SMILES COc1ccc(\C=C\C(=O)Oc2cccc3ccc(C)nc23)cc1OC

InChI Key InChIKey=CPHKRMYYWIZKOQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50065792   

TargetIntegrase(Human immunodeficiency virus type 1)
Paris-Sud University

Curated by ChEMBL
LigandPNGBDBM50065792((E)-3-(3,4-Dimethoxy-phenyl)-acrylic acid 2-methyl...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro anti-HIV integrase activity against integration (strand transfer) of target plasmid.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Paris-Sud University

Curated by ChEMBL
LigandPNGBDBM50065792((E)-3-(3,4-Dimethoxy-phenyl)-acrylic acid 2-methyl...)
Affinity DataIC50: 1.00E+5nMAssay Description:HIV integrase inhibitory potency was evaluated as IC50 on 3' processing of target DNA.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50065792((E)-3-(3,4-Dimethoxy-phenyl)-acrylic acid 2-methyl...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HIV1 integrase 3' processing activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed