BDBM50066320 CHEMBL107778::N-[3-Chloro-2-(4-nitro-phenyl)-4-oxo-azetidin-1-yl]-2-hydroxy-benzamide

SMILES Oc1ccccc1C(=O)NN1C(C(Cl)C1=O)c1ccc(cc1)[N+]([O-])=O

InChI Key InChIKey=WTESRMWBOCISMY-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50066320   

TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50066320(N-[3-Chloro-2-(4-nitro-phenyl)-4-oxo-azetidin-1-yl...)
Affinity DataIC50: 8.30E+4nMAssay Description:Inhibitory concentration was evaluated as 50% inhibition of HIV-1 integrase enzyme at strand transfer stage of DNA integration in experiment IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50066320(N-[3-Chloro-2-(4-nitro-phenyl)-4-oxo-azetidin-1-yl...)
Affinity DataIC50: 1.55E+5nMAssay Description:Inhibitory concentration was evaluated as 50% inhibition of HIV-1 integrase enzyme at strand transfer stage of DNA integration in experiment IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50066320(N-[3-Chloro-2-(4-nitro-phenyl)-4-oxo-azetidin-1-yl...)
Affinity DataIC50: 1.68E+5nMAssay Description:Inhibitory concentration was evaluated as 50% inhibition of HIV-1 integrase enzyme at 3`- processing stage of DNA integration in experiment IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50066320(N-[3-Chloro-2-(4-nitro-phenyl)-4-oxo-azetidin-1-yl...)
Affinity DataIC50: 1.92E+5nMAssay Description:Inhibitory concentration was evaluated as 50% inhibition of HIV-1 integrase enzyme at 3`- processing stage of DNA integration in experiment IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed