BDBM50066528 6-(3-Fluoro-phenyl)-2,2,4-trimethyl-1,2-dihydro-quinoline::6-(3-fluorophenyl)-2,2,4-trimethyl-1,2-dihydroquinoline::CHEMBL117585

SMILES CC1=CC(C)(C)Nc2ccc(cc12)-c1cccc(F)c1

InChI Key InChIKey=CHYOXMTWROVBDX-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50066528   

TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50066528(6-(3-fluorophenyl)-2,2,4-trimethyl-1,2-dihydroquin...)
Affinity DataKi:  182nMAssay Description:Binding affinity against Baculovirus-Expressed hPR-AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50066528(6-(3-fluorophenyl)-2,2,4-trimethyl-1,2-dihydroquin...)
Affinity DataKi:  182nMAssay Description:Displacement of [3H]progesterone from Progesterone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50066528(6-(3-fluorophenyl)-2,2,4-trimethyl-1,2-dihydroquin...)
Affinity DataIC50: 750nMAssay Description:In vitro antagonist activity against human progesterone receptor isoform B(hPR-B) in mammalian(CV-1) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed