BDBM50066558 (7-tert-Butyl-3,3-dimethyl-2,3-dihydro-benzofuran-5-yl)-(4,5-dihydro-pyrazol-1-yl)-amine::CHEMBL326295

SMILES CC(C)(C)c1cc(NN2CCC=N2)cc2c1OCC2(C)C

InChI Key InChIKey=AOLYIHGSBQNUIF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50066558   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50066558((7-tert-Butyl-3,3-dimethyl-2,3-dihydro-benzofuran-...)
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of 5-Lipoxygenase (5-LOX)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50066558((7-tert-Butyl-3,3-dimethyl-2,3-dihydro-benzofuran-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 1 (COX-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50066558((7-tert-Butyl-3,3-dimethyl-2,3-dihydro-benzofuran-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed