BDBM50066568 7-tert-Butyl-3,3-dimethyl-2,3-dihydro-benzofuran-5-carboxylic acid ethyl-methyl-amide::7-tert-butyl-N-ethyl-N,3,3-trimethyl-2,3-dihydrobenzofuran-5-carboxamide::CHEMBL117615

SMILES CCN(C)C(=O)c1cc2c(OCC2(C)C)c(c1)C(C)(C)C

InChI Key InChIKey=BMGAUIUJEJQJTO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50066568   

TargetProstaglandin G/H synthase 1(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50066568(7-tert-butyl-N-ethyl-N,3,3-trimethyl-2,3-dihydrobe...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 1 (COX-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50066568(7-tert-butyl-N-ethyl-N,3,3-trimethyl-2,3-dihydrobe...)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50066568(7-tert-butyl-N-ethyl-N,3,3-trimethyl-2,3-dihydrobe...)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of 5-Lipoxygenase (5-LOX)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed