BDBM50066570 7-tert-Butyl-3,3-dimethyl-2,3-dihydro-benzofuran-5-carboxylic acid cyclopropyl-methyl-amide::CHEMBL119433

SMILES CN(C1CC1)C(=O)c1cc2c(OCC2(C)C)c(c1)C(C)(C)C

InChI Key InChIKey=HNYCLIXXFVNJEY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50066570   

TargetProstaglandin G/H synthase 2(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50066570(7-tert-Butyl-3,3-dimethyl-2,3-dihydro-benzofuran-5...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50066570(7-tert-Butyl-3,3-dimethyl-2,3-dihydro-benzofuran-5...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 1 (COX-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50066570(7-tert-Butyl-3,3-dimethyl-2,3-dihydro-benzofuran-5...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of 5-Lipoxygenase (5-LOX)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed