BDBM50066571 7-tert-Butyl-3,3-dimethyl-5-thiophen-2-yl-2,3-dihydro-benzofuran::CHEMBL118839

SMILES CC(C)(C)c1cc(cc2c1OCC2(C)C)-c1cccs1

InChI Key InChIKey=KXCJXXZNWBYCRI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50066571   

TargetProstaglandin G/H synthase 2(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50066571(7-tert-Butyl-3,3-dimethyl-5-thiophen-2-yl-2,3-dihy...)
Affinity DataIC50: 70nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50066571(7-tert-Butyl-3,3-dimethyl-5-thiophen-2-yl-2,3-dihy...)
Affinity DataIC50: 200nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 1 (COX-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50066571(7-tert-Butyl-3,3-dimethyl-5-thiophen-2-yl-2,3-dihy...)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of 5-Lipoxygenase (5-LOX)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed