BDBM50066648 ((S)-3-Methyl-1-{3-[(S)-4-methyl-2-(pyridin-4-ylmethoxycarbonylamino)-pentanoylamino]-4-oxo-pyrrolidin-1-ylmethyl}-butyl)-carbamic acid benzyl ester::CHEMBL119285

SMILES CC(C)C[C@@H](CN1CC(NC(=O)[C@H](CC(C)C)NC(=O)OCc2ccncc2)C(=O)C1)NC(=O)OCc1ccccc1

InChI Key InChIKey=YCGCXDDZHQMZQY-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50066648   

TargetCathepsin K(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50066648(((S)-3-Methyl-1-{3-[(S)-4-methyl-2-(pyridin-4-ylme...)
Affinity DataKi:  3.5nMAssay Description:Inhibition of cathepsin KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin K(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50066648(((S)-3-Methyl-1-{3-[(S)-4-methyl-2-(pyridin-4-ylme...)
Affinity DataKi:  3.5nMAssay Description:Inhibition of cathepsin K (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50066648(((S)-3-Methyl-1-{3-[(S)-4-methyl-2-(pyridin-4-ylme...)
Affinity DataKi:  120nMAssay Description:Inhibition of cathepsin LMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin B(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50066648(((S)-3-Methyl-1-{3-[(S)-4-methyl-2-(pyridin-4-ylme...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of cathepsin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed