BDBM50066656 5-Hydroxy-1,3-bis-(4-methoxy-benzenesulfonyl)-hexahydro-pyrimidine-2-carboxylic acid hydroxyamide::CHEMBL118744

SMILES COc1ccc(cc1)S(=O)(=O)N1CC(O)CN(C1C(=O)NO)S(=O)(=O)c1ccc(OC)cc1

InChI Key InChIKey=CMBPIMDJJHAVBX-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50066656   

TargetMatrix metalloproteinase-9(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50066656(5-Hydroxy-1,3-bis-(4-methoxy-benzenesulfonyl)-hexa...)
Affinity DataIC50: 4.70nMAssay Description:Inhibition of Matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50066656(5-Hydroxy-1,3-bis-(4-methoxy-benzenesulfonyl)-hexa...)
Affinity DataIC50: 41nMAssay Description:Inhibition of Matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50066656(5-Hydroxy-1,3-bis-(4-methoxy-benzenesulfonyl)-hexa...)
Affinity DataIC50: 51nMAssay Description:Inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetMatrilysin(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50066656(5-Hydroxy-1,3-bis-(4-methoxy-benzenesulfonyl)-hexa...)
Affinity DataIC50: 366nMAssay Description:Inhibition of Matrix metalloprotease-7More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed