BDBM50066660 1,3-Bis-(4-butoxy-benzenesulfonyl)-5,5-dimethyl-hexahydro-pyrimidine-2-carboxylic acid hydroxyamide::CHEMBL334107

SMILES CCCCOc1ccc(cc1)S(=O)(=O)N1CC(C)(C)CN(C1C(=O)NO)S(=O)(=O)c1ccc(OCCCC)cc1

InChI Key InChIKey=NWAZOLPVSMLDTN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50066660   

TargetStromelysin-1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50066660(1,3-Bis-(4-butoxy-benzenesulfonyl)-5,5-dimethyl-he...)
Affinity DataIC50: 22nMAssay Description:Inhibition of Matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50066660(1,3-Bis-(4-butoxy-benzenesulfonyl)-5,5-dimethyl-he...)
Affinity DataIC50: 101nMAssay Description:Inhibition of Matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetMatrilysin(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50066660(1,3-Bis-(4-butoxy-benzenesulfonyl)-5,5-dimethyl-he...)
Affinity DataIC50: 716nMAssay Description:Inhibition of Matrix metalloprotease-7More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50066660(1,3-Bis-(4-butoxy-benzenesulfonyl)-5,5-dimethyl-he...)
Affinity DataIC50: 2.32E+3nMAssay Description:Inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed