BDBM50066776 5-Benzyl-4-trifluoromethyl-pyrrolidin-(2E)-ylideneamine; hydrochloride::CHEMBL553678

SMILES NC1=NC(Cc2ccccc2)C(C1)C(F)(F)F

InChI Key InChIKey=UQPONPWAJJACRG-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50066776   

TargetNitric oxide synthase, brain(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50066776(5-Benzyl-4-trifluoromethyl-pyrrolidin-(2E)-ylidene...)
Affinity DataIC50: 3.83E+4nMAssay Description:Inhibition of cloned (from RNA) human Neuronal nitric oxide synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50066776(5-Benzyl-4-trifluoromethyl-pyrrolidin-(2E)-ylidene...)
Affinity DataIC50: 3.83E+4nMAssay Description:Inhibition of cloned (from RNA) human Neuronal nitric oxide synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50066776(5-Benzyl-4-trifluoromethyl-pyrrolidin-(2E)-ylidene...)
Affinity DataIC50: 7.40E+4nMAssay Description:Inhibition of cloned (from RNA) human inducible nitric oxide synthase (hiNOS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50066776(5-Benzyl-4-trifluoromethyl-pyrrolidin-(2E)-ylidene...)
Affinity DataIC50: 7.40E+4nMAssay Description:Inhibition of cloned (from RNA) human inducible nitric oxide synthase (hiNOS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50066776(5-Benzyl-4-trifluoromethyl-pyrrolidin-(2E)-ylidene...)
Affinity DataIC50: 2.92E+6nMAssay Description:Inhibition of cloned (from RNA) human endothelial constitutive Endothelial nitric oxide synthase (heNOS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50066776(5-Benzyl-4-trifluoromethyl-pyrrolidin-(2E)-ylidene...)
Affinity DataIC50: 2.92E+6nMAssay Description:Inhibition of cloned (from RNA) human endothelial constitutive Endothelial nitric oxide synthase (heNOS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed