BDBM50067000 (3aS,6R)-6-Allyl-4-(naphthalene-1-sulfonyl)-5-oxo-hexahydro-pyrrolo[3,2-b]pyrrole-1-carboxylic acid benzyl ester::CHEMBL127085

SMILES C=CC[C@@H]1C2[C@H](CCN2C(=O)OCc2ccccc2)N(C1=O)S(=O)(=O)c1cccc2ccccc12

InChI Key InChIKey=TVSPRIRMHVAWPW-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50067000   

TargetNeutrophil elastase(Human)
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50067000((3aS,6R)-6-Allyl-4-(naphthalene-1-sulfonyl)-5-oxo-...)
Affinity DataIC50: 88nMAssay Description:The compound was tested for inhibition of human neutrophil elastase enzyme with a pre-incubation time of 40 min.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50067000((3aS,6R)-6-Allyl-4-(naphthalene-1-sulfonyl)-5-oxo-...)
Affinity DataIC50: 1.00E+5nMAssay Description:The compound was tested for inhibition of thrombin with a pre-incubation time of 15 min.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsinogen A(Bovine)
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50067000((3aS,6R)-6-Allyl-4-(naphthalene-1-sulfonyl)-5-oxo-...)
Affinity DataIC50: 1.15E+4nMAssay Description:The compound was tested for inhibition of Chymotrypsinogen with a pre-incubation time of 15 minMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50067000((3aS,6R)-6-Allyl-4-(naphthalene-1-sulfonyl)-5-oxo-...)
Affinity DataIC50: 1.00E+5nMAssay Description:The compound was tested for inhibition of human neutrophil elastase enzyme with a pre-incubation time of 0 min.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed