BDBM50067001 (3aS,6R)-6-Allyl-5-oxo-hexahydro-pyrrolo[3,2-b]pyrrole-1-carboxylic acid benzyl ester::CHEMBL2367635::benzyl (3aS,6aR)-6-allyl-5-oxohexahydropyrrolo[3,2-b]pyrrole-1(2H)-carboxylate

SMILES [H][C@]12CCN(C(=O)OCc3ccccc3)[C@]1([H])[C@@H](CC=C)C(=O)N2

InChI Key InChIKey=WQCQPTJPTWXLKJ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50067001   

TargetNeutrophil elastase(Human)
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50067001(CHEMBL2367635 | (3aS,6R)-6-Allyl-5-oxo-hexahydro-p...)
Affinity DataIC50: 500nMAssay Description:In vitro inhibitory activity against human neutrophil elastase (HNE)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50067001(CHEMBL2367635 | (3aS,6R)-6-Allyl-5-oxo-hexahydro-p...)
Affinity DataIC50: 5.00E+5nMAssay Description:The compound was tested for inhibition of human neutrophil elastase enzyme with a pre-incubation time of 40 min.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsinogen A(Bovine)
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50067001(CHEMBL2367635 | (3aS,6R)-6-Allyl-5-oxo-hexahydro-p...)
Affinity DataIC50: 1.00E+5nMAssay Description:The compound was tested for inhibition of Chymotrypsinogen with a pre-incubation time of 15 min.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50067001(CHEMBL2367635 | (3aS,6R)-6-Allyl-5-oxo-hexahydro-p...)
Affinity DataIC50: 1.00E+5nMAssay Description:The compound was tested for inhibition of human neutrophil elastase enzyme with a pre-incubation time of 40 min.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50067001(CHEMBL2367635 | (3aS,6R)-6-Allyl-5-oxo-hexahydro-p...)
Affinity DataIC50: 1.00E+5nMAssay Description:The compound was tested for inhibition of thrombin with a pre-incubation time of 15 min.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed