BDBM50067799 CHEMBL3402139

SMILES CCC(CC)c1ccc(CN2c3ccccc3N(CCCC(=O)N3CCCC3)S2(=O)=O)cc1

InChI Key InChIKey=YCEJENREJIKZIK-UHFFFAOYSA-N

Data  2 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50067799   

TargetNuclear receptor ROR-gamma(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50067799(CHEMBL3402139)
Affinity DataIC50: 1.00E+3nMAssay Description:Inverse agonist activity at RORC in human PBMCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50067799(CHEMBL3402139)
Affinity DataKd:  1.50E+3nMAssay Description:Binding affinity to RORC-SRC2 fusion construct (unknown origin) by TAMRA-labeled active site probe based fluorescence polarization competition bindin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50067799(CHEMBL3402139)
Affinity DataIC50: 3.40E+3nMAssay Description:Inverse agonist activity at RORC ligand binding domain (unknown origin) expressed in HEK293 cells transfected with GAL4 promoter by luciferase report...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed