BDBM50067809 3-Methyl-5-phenyl-1,2,3,4,5,6-hexahydro-azepino[4,5-b]indole::CHEMBL23529

SMILES CN1CCc2c([nH]c3ccccc23)C(C1)c1ccccc1

InChI Key InChIKey=MIBJALISUVUJMQ-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50067809   

TargetSodium-dependent dopamine transporter(Rat)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50067809(3-Methyl-5-phenyl-1,2,3,4,5,6-hexahydro-azepino[4,...)
Affinity DataIC50: 180nMAssay Description:relative affinity against dopamine transporter using WIN-35428 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50067809(3-Methyl-5-phenyl-1,2,3,4,5,6-hexahydro-azepino[4,...)
Affinity DataIC50: 190nMAssay Description:relative affinity against serotonin transporter using RTI-55 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50067809(3-Methyl-5-phenyl-1,2,3,4,5,6-hexahydro-azepino[4,...)
Affinity DataIC50: 3.10E+3nMAssay Description:Relative affinity against Opioid receptor mu 1 in thalamus using [3H]DAMGO as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Rat)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50067809(3-Methyl-5-phenyl-1,2,3,4,5,6-hexahydro-azepino[4,...)
Affinity DataIC50: 4.20E+3nMAssay Description:relative affinity against Dopamine receptor D3 in ventral striatum using [3H](+)-7-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50067809(3-Methyl-5-phenyl-1,2,3,4,5,6-hexahydro-azepino[4,...)
Affinity DataIC50: 2.00E+4nMAssay Description:Relative affinity for Dopamine receptor D1 in striatum using [3H]SCH-23390More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Rat)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50067809(3-Methyl-5-phenyl-1,2,3,4,5,6-hexahydro-azepino[4,...)
Affinity DataIC50: 2.12E+4nMAssay Description:relative affinity against Opioid receptor kappa 1 in insular Ctx using [3H]U-69593 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50067809(3-Methyl-5-phenyl-1,2,3,4,5,6-hexahydro-azepino[4,...)
Affinity DataIC50: 2.72E+4nMAssay Description:relative affinity against Dopamine receptor D2 in striatum using [3H]YM-09151-2 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed