BDBM50067859 CHEMBL141808::N*6*-(3,4,5-Trimethoxy-benzyl)-pyrido[3,2-d]pyrimidine-2,4,6-triamine

SMILES COc1cc(CNc2ccc3nc(N)nc(N)c3n2)cc(OC)c1OC

InChI Key InChIKey=PSSLUZRUBJMOPG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50067859   

TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50067859(N*6*-(3,4,5-Trimethoxy-benzyl)-pyrido[3,2-d]pyrimi...)
Affinity DataIC50: 490nMAssay Description:Inhibitory activity against dihydrofolate reductase (DHFR) from Toxoplasma gondiiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50067859(N*6*-(3,4,5-Trimethoxy-benzyl)-pyrido[3,2-d]pyrimi...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibitory activity against dihydrofolate reductase (DHFR) from rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50067859(N*6*-(3,4,5-Trimethoxy-benzyl)-pyrido[3,2-d]pyrimi...)
Affinity DataIC50: 2.94E+4nMAssay Description:Inhibitory activity against dihydrofolate reductase (DHFR) from Pneumocystis cariniiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed