BDBM50067891 5-chlorothiophen-2-ylboronic acid::5-chlorothiphene 2-boronic acid::CHEMBL142592

SMILES OB(O)c1ccc(Cl)s1

InChI Key InChIKey=JFCLNCVCDFUJPO-UHFFFAOYSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50067891   

TargetBeta-lactamase(Escherichia coli (strain K12))
Northwestern University Medical School

Curated by ChEMBL
LigandPNGBDBM50067891(5-chlorothiophen-2-ylboronic acid | 5-chlorothiphe...)
Affinity DataIC50: 2.00E+3nMAssay Description:Compound was tested for its specificity against AmpC beta-lactamaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrypsin-2(Human)
Northwestern University Medical School

Curated by ChEMBL
LigandPNGBDBM50067891(5-chlorothiophen-2-ylboronic acid | 5-chlorothiphe...)
Affinity DataIC50: 2.00E+5nMAssay Description:Compound was tested for its specificity against beta-trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsinogen A(Bovine)
Northwestern University Medical School

Curated by ChEMBL
LigandPNGBDBM50067891(5-chlorothiophen-2-ylboronic acid | 5-chlorothiphe...)
Affinity DataIC50: 1.00E+5nMAssay Description:Compound was tested for its specificity against alpha-chymotrypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Human)
Tokushima University

Curated by ChEMBL
LigandPNGBDBM50067891(5-chlorothiophen-2-ylboronic acid | 5-chlorothiphe...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human DAO using D-serine as substrate after 20 mins in presence of FADMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetBeta-lactamase(Escherichia coli (strain K12))
Northwestern University Medical School

Curated by ChEMBL
LigandPNGBDBM50067891(5-chlorothiophen-2-ylboronic acid | 5-chlorothiphe...)
Affinity DataKi:  410nMAssay Description:Inhibitory activity against Escherichia coli AmpC beta-lactamase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed