BDBM50067898 3-(5-(dimethylamino)naphthalene-1-sulfonamido)phenylboronic acid::CHEMBL140740::m(dansylamidophenyl)boronic acid

SMILES CN(C)c1cccc2c(cccc12)S(=O)(=O)Nc1cccc(c1)B(O)O

InChI Key InChIKey=TYXMKSYBCDTGDU-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50067898   

TargetBeta-lactamase(Escherichia coli (strain K12))
Northwestern University Medical School

Curated by ChEMBL
LigandPNGBDBM50067898(3-(5-(dimethylamino)naphthalene-1-sulfonamido)phen...)
Affinity DataIC50: 5.00E+3nMAssay Description:Compound was tested for its specificity against AmpC beta-lactamaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsinogen A(Bovine)
Northwestern University Medical School

Curated by ChEMBL
LigandPNGBDBM50067898(3-(5-(dimethylamino)naphthalene-1-sulfonamido)phen...)
Affinity DataIC50: 1.00E+5nMAssay Description:Compound was tested for its specificity against alpha-chymotrypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrypsin-2(Human)
Northwestern University Medical School

Curated by ChEMBL
LigandPNGBDBM50067898(3-(5-(dimethylamino)naphthalene-1-sulfonamido)phen...)
Affinity DataIC50: 1.00E+5nMAssay Description:Compound was tested for its specificity against beta-trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-lactamase(Escherichia coli (strain K12))
Northwestern University Medical School

Curated by ChEMBL
LigandPNGBDBM50067898(3-(5-(dimethylamino)naphthalene-1-sulfonamido)phen...)
Affinity DataKi:  1.30E+3nMAssay Description:Inhibitory activity against Escherichia coli AmpC beta-lactamase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed