BDBM50068120 CHEMBL3402253

SMILES Cc1ccc(cc1)S(=O)(=O)NC(=O)[C@@H]1[C@H](C(O)=O)[C@@]2(Cl)[C@@](O)(Cl)[C@](O)(Cl)[C@@]1(Cl)C2(Cl)Cl

InChI Key

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50068120   

TargetCarbonic anhydrase 1(Human)
Ataturk University

Curated by ChEMBL
LigandPNGBDBM50068120(CHEMBL3402253)
Affinity DataKi:  52nMAssay Description:Inhibition of human CA-1 using p-nitro-phenylacetate as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Ataturk University

Curated by ChEMBL
LigandPNGBDBM50068120(CHEMBL3402253)
Affinity DataKi:  58nMAssay Description:Inhibition of human CA-2 using p-nitro-phenylacetate as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Ataturk University

Curated by ChEMBL
LigandPNGBDBM50068120(CHEMBL3402253)
Affinity DataIC50: 120nMAssay Description:Inhibition of human CA-2 using p-nitro-phenylacetate as substrate after 3 mins by UV-Vis spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Ataturk University

Curated by ChEMBL
LigandPNGBDBM50068120(CHEMBL3402253)
Affinity DataIC50: 171nMAssay Description:Inhibition of human CA-1 using p-nitro-phenylacetate as substrate after 3 mins by UV-Vis spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed