BDBM50068272 CHEMBL3403353

SMILES CCn1c(NC2CCC2)nc2ccsc2c1=O

InChI Key InChIKey=VLGHUVDPAFTFQM-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50068272   

TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Human)
Kaken Pharmaceutical

Curated by ChEMBL

LigandBDBM50068272(CHEMBL3403353)Copy SMILESCopy InChI

Affinity DataIC50: 300nMAssay Description:Inhibition of human PDE7A expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
4/13/2016
Entry Details Article
Copy Entry DOIPubMed
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TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Kaken Pharmaceutical

Curated by ChEMBL

LigandBDBM50068272(CHEMBL3403353)Copy SMILESCopy InChI

Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of human PDE4B expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
4/13/2016
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL