BDBM50068651 2-[2-Amino-3-(4-hydroxy-phenyl)-propionyl]-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid [1-((1R,2S)-1-carbamoyl-2-phenyl-propylcarbamoyl)-2-phenyl-ethyl]-amide::CHEMBL2371024

SMILES C[C@H]1[C@@H](N(Cc2ccccc12)C(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(O)=O

InChI Key InChIKey=FHYMFNMJTKMYQF-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50068651   

TargetDelta-type opioid receptor(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50068651(2-[2-Amino-3-(4-hydroxy-phenyl)-propionyl]-1,2,3,4...)
Affinity DataKi:  543nMAssay Description:Binding affinity towards human Opioid receptor delta 1 on NxG108CC15 (human neuroglioblastoma) cell membranes by [3H]DPDPE displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50068651(2-[2-Amino-3-(4-hydroxy-phenyl)-propionyl]-1,2,3,4...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity towards Opioid receptor kappa 1 on guinea pig cerebellum membranes by [3H]U-69593 displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50068651(2-[2-Amino-3-(4-hydroxy-phenyl)-propionyl]-1,2,3,4...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity towards Opioid receptor mu 1 on rat forebrain membranes by [3H]sufentanil displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50068651(2-[2-Amino-3-(4-hydroxy-phenyl)-propionyl]-1,2,3,4...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity towards Opioid receptor mu 1 on rat forebrain membranes by [3H]sufentanil displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2012
Entry Details Article
PubMed