BDBM50068659 2-[2-Amino-3-(4-hydroxy-phenyl)-propionyl]-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid [(1S,2S)-1-(1-carbamoyl-2-phenyl-ethylcarbamoyl)-2-phenyl-propyl]-amide::CHEMBL2369139

SMILES C[C@H]([C@@H](NC(=O)[C@@H]1Cc2ccccc2CN1C(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O)c1ccccc1

InChI Key InChIKey=LHXYNKYCJVHHFO-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50068659   

TargetDelta-type opioid receptor(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50068659(2-[2-Amino-3-(4-hydroxy-phenyl)-propionyl]-1,2,3,4...)
Affinity DataKi:  0.5nMAssay Description:Binding affinity towards human Opioid receptor delta 1 on NxG108CC15 (human neuroglioblastoma) cell membranes by [3H]DPDPE displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50068659(2-[2-Amino-3-(4-hydroxy-phenyl)-propionyl]-1,2,3,4...)
Affinity DataKi:  1.19E+3nMAssay Description:Binding affinity towards Opioid receptor kappa 1 on guinea pig cerebellum membranes by [3H]U-69593 displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50068659(2-[2-Amino-3-(4-hydroxy-phenyl)-propionyl]-1,2,3,4...)
Affinity DataKi:  1.19E+3nMAssay Description:Binding affinity towards Opioid receptor mu 1 on rat forebrain membranes by [3H]sufentanil displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2012
Entry Details Article
PubMed