BDBM50068797 CHEMBL3402395

SMILES Oc1cccc(Nc2nc(Nc3ccc(OCC#N)cc3)ncc2F)c1

InChI Key InChIKey=FGVFBIWZADOJDR-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50068797   

TargetTyrosine-protein kinase SYK(Human)
Amarit Bioscience

Curated by ChEMBL
LigandPNGBDBM50068797(CHEMBL3402395)
Affinity DataEC50:  450nMAssay Description:Inhibition of SYK in human mast cell cultures assessed as reduction in IgE-induced FCepsilonR1 mediated degranulation by tryptase release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Amarit Bioscience

Curated by ChEMBL
LigandPNGBDBM50068797(CHEMBL3402395)
Affinity DataEC50:  1.00E+4nMAssay Description:Inhibition of SYK in human mast cell cultures assessed as reduction in ionomycin-induced calcium mobilization mediated degranulation by tryptase rele...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed