BDBM50069241 CHEMBL405162::Spongistatin-1

SMILES CO[C@H]1C[C@H]2CC(=O)[C@@H](C)[C@@H](OC(C)=O)[C@H](C)C(=C)C[C@H]3C[C@](C)(O)C[C@@]4(C[C@H](C[C@H](CC(=O)O[C@@H]5[C@@H](C)[C@@H](O[C@H](CC(=C)C(C)[C@H](O)\C=C\C(Cl)=C)[C@H]5O)[C@H](O)[C@@]5(O)C[C@H](O)[C@@H](C)[C@@H](CCC\C=C/[C@H]6C[C@H](O)C[C@@](C1)(C6)O2)O5)O4)OC(C)=O)O3

InChI Key InChIKey=HAOCRCFHEPRQOY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50069241   

TargetTubulin alpha-1A chain(Pig)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50069241(Spongistatin-1 | CHEMBL405162)
Affinity DataIC50: 3.60E+3nMAssay Description:Compound was tested for its ability to inhibit the glutamate induced polymerization of tubulinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed