BDBM50069483 CHEMBL356281::N-(7-Bromo-2,3-dioxo-1,2,3,4-tetrahydro-quinoxalin-5-ylmethyl)-2-thiophen-3-yl-acetamide

SMILES Brc1cc(CNC(=O)Cc2ccsc2)c2[nH]c(=O)c(=O)[nH]c2c1

InChI Key InChIKey=ZPZMPJXQGUTTFQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50069483   

TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50069483(N-(7-Bromo-2,3-dioxo-1,2,3,4-tetrahydro-quinoxalin...)
Affinity DataIC50: 10nMAssay Description:In vitro binding assay for the displacement of [3H]MDL-105519 from the glycine-site of NMDA receptorsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2A(Human)
Central South University

Curated by ChEMBL
LigandPNGBDBM50069483(N-(7-Bromo-2,3-dioxo-1,2,3,4-tetrahydro-quinoxalin...)
Affinity DataIC50: 1.13E+4nMAssay Description:Displacement of [3H]AMPA from NMDA receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetGlutamate receptor ionotropic, NMDA 2A(Human)
Central South University

Curated by ChEMBL
LigandPNGBDBM50069483(N-(7-Bromo-2,3-dioxo-1,2,3,4-tetrahydro-quinoxalin...)
Affinity DataIC50: 10nMAssay Description:Displacement of [3H]MDL from NMDA receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed