BDBM50069568 1-Benzo[1,3]dioxol-5-ylmethyl-4-(4-methoxy-phenyl)-2-oxo-1,2-dihydro-benzo[4,5]furo[3,2-b]pyridine-3-carboxylic acid::CHEMBL73506

SMILES COc1ccc(cc1)-c1c(C(O)=O)c(=O)n(Cc2ccc3OCOc3c2)c2c3ccccc3oc12

InChI Key InChIKey=OMGOSUSSSZSHGY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50069568   

TargetEndothelin receptor type B(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50069568(1-Benzo[1,3]dioxol-5-ylmethyl-4-(4-methoxy-phenyl)...)
Affinity DataIC50: 440nMAssay Description:Inhibition of [125I]ET1 binding to porcine kidney inner medulla membrane Endothelin B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM50069568(1-Benzo[1,3]dioxol-5-ylmethyl-4-(4-methoxy-phenyl)...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of [125I]ET1 binding to rat aorta membrane Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed