BDBM50069828 4-Methyl-3-((S)-1-methyl-pyrrolidin-2-ylmethoxy)-pyridine::CHEMBL315212

SMILES CN1CCC[C@H]1COc1cnccc1C

InChI Key InChIKey=WYBSJZOMLJBUFE-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50069828   

TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50069828(4-Methyl-3-((S)-1-methyl-pyrrolidin-2-ylmethoxy)-p...)
Affinity DataKi:  4.10nMAssay Description:Binding affinity towards nAChR (alpha4-beta2) by the displacement of [3H](-)-cytisine in whole rat brain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50069828(4-Methyl-3-((S)-1-methyl-pyrrolidin-2-ylmethoxy)-p...)
Affinity DataEC50:  2.10E+3nMAssay Description:Stimulation of cation efflux in human nAChR alpha4-beta2 expressing K177 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed