BDBM50070163 CHEMBL417250::N-[4-(4-{2-[(S)-2-Hydroxy-3-(4-hydroxy-phenoxy)-propylamino]-ethyl}-phenylsulfamoyl)-phenyl]-benzamide

SMILES O[C@@H](CNCCc1ccc(NS(=O)(=O)c2ccc(NC(=O)c3ccccc3)cc2)cc1)COc1ccc(O)cc1

InChI Key InChIKey=QSWLIXFWXBYMEU-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50070163   

TargetBeta-3 adrenergic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50070163(N-[4-(4-{2-[(S)-2-Hydroxy-3-(4-hydroxy-phenoxy)-pr...)
Affinity DataEC50:  2.30nMAssay Description:Agonist activity towards human Beta-3 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50070163(N-[4-(4-{2-[(S)-2-Hydroxy-3-(4-hydroxy-phenoxy)-pr...)
Affinity DataIC50: 110nMAssay Description:In vitro affinity at Beta-2 adrenergic receptor in the presence of [125I]iodocyanopindolol.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50070163(N-[4-(4-{2-[(S)-2-Hydroxy-3-(4-hydroxy-phenoxy)-pr...)
Affinity DataIC50: 220nMAssay Description:In vitro affinity at Beta-1 adrenergic receptor in the presence of [125I]iodocyanopindolol.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed