BDBM50070184 ((6aR,9S,10aR)-7-Methyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinolin-9-ylmethyl)-carbamic acid benzyl ester::(7-Methyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinolin-9-ylmethyl)-carbamic acid benzyl ester::CHEMBL13816

SMILES CN1C[C@H](CNC(=O)OCc2ccccc2)C[C@H]2[C@H]1Cc1c[nH]c3cccc2c13

InChI Key InChIKey=REJFPXMKRRYBSC-UHFFFAOYSA-N

Data  5 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50070184   

Target5-hydroxytryptamine receptor 7(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50070184(((6aR,9S,10aR)-7-Methyl-4,6,6a,7,8,9,10,10a-octahy...)
Affinity DataKi:  6.40nMAssay Description:Displacement of [3H]5-HT from human 5-hydroxytryptamine 7 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50070184(((6aR,9S,10aR)-7-Methyl-4,6,6a,7,8,9,10,10a-octahy...)
Affinity DataKi:  60nMAssay Description:Binding affinity towards rat 5-hydroxytryptamine 7 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50070184(((6aR,9S,10aR)-7-Methyl-4,6,6a,7,8,9,10,10a-octahy...)
Affinity DataIC50: 60nMAssay Description:Displacement of [3H]8-OH-DPAT from 5-hydroxytryptamine 1A receptor in rat hippocampusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50070184(((6aR,9S,10aR)-7-Methyl-4,6,6a,7,8,9,10,10a-octahy...)
Affinity DataIC50: 150nMAssay Description:Displacement of [3H]spiroperidol from D2 receptor in rat striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50070184(((6aR,9S,10aR)-7-Methyl-4,6,6a,7,8,9,10,10a-octahy...)
Affinity DataIC50: 250nMAssay Description:Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptor in rat pre frontal cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50070184(((6aR,9S,10aR)-7-Methyl-4,6,6a,7,8,9,10,10a-octahy...)
Affinity DataIC50: 390nMAssay Description:Displacement of [3H]yohimbine from Alpha-2 adrenergic receptor in rat frontal cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50070184(((6aR,9S,10aR)-7-Methyl-4,6,6a,7,8,9,10,10a-octahy...)
Affinity DataKi:  400nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 6 receptor was evaluated using [3H]-LSD as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50070184(((6aR,9S,10aR)-7-Methyl-4,6,6a,7,8,9,10,10a-octahy...)
Affinity DataKi:  630nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 5A receptor was evaluated using [3H]-5-CT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50070184(((6aR,9S,10aR)-7-Methyl-4,6,6a,7,8,9,10,10a-octahy...)
Affinity DataKi:  1.00E+3nMAssay Description:Binding affinity for rodent 5-hydroxytryptamine 5A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50070184(((6aR,9S,10aR)-7-Methyl-4,6,6a,7,8,9,10,10a-octahy...)
Affinity DataIC50: 1.42E+3nMAssay Description:Displacement of [3H]SCH-23390 from D1 receptor in rat striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50070184(((6aR,9S,10aR)-7-Methyl-4,6,6a,7,8,9,10,10a-octahy...)
Affinity DataIC50: 3.33E+3nMAssay Description:Displacement of [3H]prazosin from Alpha-1 adrenergic receptor in rat frontal cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed