BDBM50070187 1-Acetyl-3-((6aR,9S,10aR)-3-tert-butyl-7-methyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinolin-9-ylmethyl)-thiourea::CHEMBL14020

SMILES CN1C[C@H](CNC(=S)NC(C)=O)C[C@H]2[C@H]1Cc1c[nH]c3c(ccc2c13)C(C)(C)C

InChI Key InChIKey=KUUURIADAZPOIK-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50070187   

TargetSerotonin 2 (5-HT2) receptor(Rat)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50070187(1-Acetyl-3-((6aR,9S,10aR)-3-tert-butyl-7-methyl-4,...)
Affinity DataIC50: 3nMAssay Description:Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptor in rat pre frontal cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50070187(1-Acetyl-3-((6aR,9S,10aR)-3-tert-butyl-7-methyl-4,...)
Affinity DataIC50: 450nMAssay Description:Displacement of [3H]yohimbine from Alpha-2 adrenergic receptor in rat frontal cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50070187(1-Acetyl-3-((6aR,9S,10aR)-3-tert-butyl-7-methyl-4,...)
Affinity DataIC50: 780nMAssay Description:Displacement of [3H]prazosin from Alpha-1 adrenergic receptor in rat frontal cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50070187(1-Acetyl-3-((6aR,9S,10aR)-3-tert-butyl-7-methyl-4,...)
Affinity DataIC50: 930nMAssay Description:Displacement of [3H]8-OH-DPAT from 5-hydroxytryptamine 1A receptor in rat hippocampusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50070187(1-Acetyl-3-((6aR,9S,10aR)-3-tert-butyl-7-methyl-4,...)
Affinity DataIC50: 1.41E+3nMAssay Description:Displacement of [3H]spiroperidol from D2 receptor in rat striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50070187(1-Acetyl-3-((6aR,9S,10aR)-3-tert-butyl-7-methyl-4,...)
Affinity DataIC50: 4.58E+3nMAssay Description:Displacement of [3H]SCH-23390 from D1 receptor in rat striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed