BDBM50070253 (2R,4S)-4-Hydroxy-2-isobutyl-5-mercapto-pentanoic acid ((S)-2,2-dimethyl-1-methylcarbamoyl-propyl)-amide::CHEMBL16630

SMILES CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)C[C@H](O)CS)C(C)(C)C

InChI Key InChIKey=UOLDAWOAHWACHY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50070253   

TargetMatrix metalloproteinase-9(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50070253((2R,4S)-4-Hydroxy-2-isobutyl-5-mercapto-pentanoic ...)
Affinity DataIC50: 8nMAssay Description:Inhibition of matrix metalloprotease-9, gelatinase-BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50070253((2R,4S)-4-Hydroxy-2-isobutyl-5-mercapto-pentanoic ...)
Affinity DataIC50: 11nMAssay Description:Inhibition of matrix metalloprotease-1, Collagenase-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50070253((2R,4S)-4-Hydroxy-2-isobutyl-5-mercapto-pentanoic ...)
Affinity DataIC50: 470nMAssay Description:Inhibition of matrix metalloprotease-3, stromelysin-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed