BDBM50070351 1-(1-{3-[1-Benzoyl-3-(3,4-dichloro-phenyl)-piperidin-3-yl]-propyl}-4-phenyl-piperidin-4-yl)-ethanone::CHEMBL27463

SMILES CC(=O)C1(CCN(CCCC2(CCCN(C2)C(=O)c2ccccc2)c2ccc(Cl)c(Cl)c2)CC1)c1ccccc1

InChI Key InChIKey=NCJWLSWXMPGOIS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50070351   

TargetNeuromedin-K receptor(Human)
Merck Sharp Laboratory

Curated by ChEMBL
LigandPNGBDBM50070351(1-(1-{3-[1-Benzoyl-3-(3,4-dichloro-phenyl)-piperid...)
Affinity DataIC50: 1.5nMAssay Description:Compound was evaluated for its ability to displace [3H]NKB binding in hNK3 receptors expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Merck Sharp Laboratory

Curated by ChEMBL
LigandPNGBDBM50070351(1-(1-{3-[1-Benzoyl-3-(3,4-dichloro-phenyl)-piperid...)
Affinity DataIC50: 389nMAssay Description:Compound was evaluated for affinity towards human Neurokinin NK2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Merck Sharp Laboratory

Curated by ChEMBL
LigandPNGBDBM50070351(1-(1-{3-[1-Benzoyl-3-(3,4-dichloro-phenyl)-piperid...)
Affinity DataIC50: 460nMAssay Description:Compound was evaluated for affinity towards human Neurokinin NK1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed