BDBM50070355 3-(3,4-dichlorophenyl)-3-{3-[1-methylsulfonylspiro[2,3-dihydro-1H-indole-3,4'-(hexahydropyridine)]-1-yl]propyl}hexahydro-1-pyridinyl-phenylmethanone::CHEMBL281481

SMILES CS(=O)(=O)N1CC2(CCN(CCCC3(CCCN(C3)C(=O)c3ccccc3)c3ccc(Cl)c(Cl)c3)CC2)c2ccccc12

InChI Key InChIKey=WAACBTLXCIQAPC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50070355   

TargetNeuromedin-K receptor(Human)
Merck Sharp Laboratory

Curated by ChEMBL
LigandPNGBDBM50070355(3-(3,4-dichlorophenyl)-3-{3-[1-methylsulfonylspiro...)
Affinity DataIC50: 1.20nMAssay Description:Compound was evaluated for its ability to displace [3H]NKB binding in hNK3 receptors expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Merck Sharp Laboratory

Curated by ChEMBL
LigandPNGBDBM50070355(3-(3,4-dichlorophenyl)-3-{3-[1-methylsulfonylspiro...)
Affinity DataIC50: 177nMAssay Description:Compound was evaluated for affinity towards human Neurokinin NK2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Merck Sharp Laboratory

Curated by ChEMBL
LigandPNGBDBM50070355(3-(3,4-dichlorophenyl)-3-{3-[1-methylsulfonylspiro...)
Affinity DataIC50: 497nMAssay Description:Compound was evaluated for affinity towards human Neurokinin NK1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed