BDBM50070358 8-{3-[1-Benzyl-3-(3,4-dichloro-phenyl)-6-oxo-piperidin-3-yl]-propyl}-3-phenyl-2,3,8-triaza-spiro[4.5]decan-1-one::CHEMBL281019

SMILES Clc1ccc(cc1Cl)C1(CCCN2CCC3(CN(NC3=O)c3ccccc3)CC2)CCC(=O)N(Cc2ccccc2)C1

InChI Key InChIKey=VIGYJJFBPARTJM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50070358   

TargetSubstance-K receptor(Human)
Merck Sharp Laboratory

Curated by ChEMBL
LigandPNGBDBM50070358(8-{3-[1-Benzyl-3-(3,4-dichloro-phenyl)-6-oxo-piper...)
Affinity DataIC50: 2.5nMAssay Description:Compound was evaluated for affinity towards human Neurokinin NK2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed
TargetNeuromedin-K receptor(Human)
Merck Sharp Laboratory

Curated by ChEMBL
LigandPNGBDBM50070358(8-{3-[1-Benzyl-3-(3,4-dichloro-phenyl)-6-oxo-piper...)
Affinity DataIC50: 127nMAssay Description:Compound was evaluated for its ability to displace [3H]NKB binding in hNK3 receptors expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Merck Sharp Laboratory

Curated by ChEMBL
LigandPNGBDBM50070358(8-{3-[1-Benzyl-3-(3,4-dichloro-phenyl)-6-oxo-piper...)
Affinity DataIC50: 892nMAssay Description:Compound was evaluated for affinity towards human Neurokinin NK1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed