BDBM50070360 3-(3,4-dichlorophenyl)-3-[3-spiro[2,3-dihydro-1H-indene-1,4'-(hexahydropyridine)]-1-ylpropyl]hexahydro-1-pyridinyl-phenylmethanone::CHEMBL26831

SMILES Clc1ccc(cc1Cl)C1(CCCN2CCC3(CCc4ccccc34)CC2)CCCN(C1)C(=O)c1ccccc1

InChI Key InChIKey=MUZRICFSRACWJI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50070360   

TargetNeuromedin-K receptor(Human)
Merck Sharp Laboratory

Curated by ChEMBL
LigandPNGBDBM50070360(3-(3,4-dichlorophenyl)-3-[3-spiro[2,3-dihydro-1H-i...)
Affinity DataIC50: 2.60nMAssay Description:Compound was evaluated for its ability to displace [3H]NKB binding in hNK3 receptors expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Merck Sharp Laboratory

Curated by ChEMBL
LigandPNGBDBM50070360(3-(3,4-dichlorophenyl)-3-[3-spiro[2,3-dihydro-1H-i...)
Affinity DataIC50: 204nMAssay Description:Compound was evaluated for affinity towards human Neurokinin NK2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Merck Sharp Laboratory

Curated by ChEMBL
LigandPNGBDBM50070360(3-(3,4-dichlorophenyl)-3-[3-spiro[2,3-dihydro-1H-i...)
Affinity DataIC50: 272nMAssay Description:Compound was evaluated for affinity towards human Neurokinin NK1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed