BDBM50070408 2-[8-(4-Methyl-piperazin-1-yl)-naphthalen-2-yloxy]-1-(4-{2-[8-(4-methyl-piperazin-1-yl)-naphthalen-2-yloxy]-acetyl}-piperazin-1-yl)-ethanone::CHEMBL285402

SMILES CN1CCN(CC1)c1cccc2ccc(OCC(=O)N3CCN(CC3)C(=O)COc3ccc4cccc(N5CCN(C)CC5)c4c3)cc12

InChI Key InChIKey=VTQFKNOCGMLKLQ-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50070408   

Target5-hydroxytryptamine receptor 1D(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50070408(2-[8-(4-Methyl-piperazin-1-yl)-naphthalen-2-yloxy]...)
Affinity DataKi:  1.20nMAssay Description:Binding affinity was evaluated at human recombinant 5-hydroxytryptamine 1D receptor using [3H]-5-CT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50070408(2-[8-(4-Methyl-piperazin-1-yl)-naphthalen-2-yloxy]...)
Affinity DataKi:  2.60nMAssay Description:The intrinsic activity was evaluated for its ability to inhibit forskolin-stimulated c-AMP formation mediated by cloned 5-hydroxytryptamine 1B recept...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50070408(2-[8-(4-Methyl-piperazin-1-yl)-naphthalen-2-yloxy]...)
Affinity DataKi:  4nMAssay Description:Binding affinity was evaluated at human recombinant 5-hydroxytryptamine 1A receptor using [3H]8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed