BDBM50070460 (2S,3R)-2-Allyl-N*1*-hydroxy-3-isobutyl-2-methyl-N*4*-((S)-1-methylcarbamoyl-2-phenyl-ethyl)-succinamide::CHEMBL35348

SMILES CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)[C@](C)(CC=C)C(=O)NO

InChI Key InChIKey=MVNUXJNXEWKALY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50070460   

TargetInterstitial collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50070460((2S,3R)-2-Allyl-N*1*-hydroxy-3-isobutyl-2-methyl-N...)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50070460((2S,3R)-2-Allyl-N*1*-hydroxy-3-isobutyl-2-methyl-N...)
Affinity DataIC50: 4.20nMAssay Description:Inhibition of Matrix metalloprotease-2 (MMP-2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50070460((2S,3R)-2-Allyl-N*1*-hydroxy-3-isobutyl-2-methyl-N...)
Affinity DataIC50: 25nMAssay Description:Inhibition of Matrix metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed