BDBM50070596 CHEMBL282549::N-Methyl-N-{3-[2-(pyridin-4-ylamino)-ethoxy]-phenyl}-benzenesulfonamide

SMILES CN(c1cccc(OCCNc2ccncc2)c1)S(=O)(=O)c1ccccc1

InChI Key InChIKey=QNSIKAKIUZRPEO-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50070596   

TargetProthrombin(Human)
Thrombosis Research Institute

Curated by ChEMBL
LigandPNGBDBM50070596(N-Methyl-N-{3-[2-(pyridin-4-ylamino)-ethoxy]-pheny...)
Affinity DataKi:  63nMAssay Description:Binding affinity towards human thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Thrombosis Research Institute

Curated by ChEMBL
LigandPNGBDBM50070596(N-Methyl-N-{3-[2-(pyridin-4-ylamino)-ethoxy]-pheny...)
Affinity DataKi:  70nMAssay Description:Compound was tested in vitro for its ability to inhibit serine protease thrombin using succinyl-Ala-p-nitroanilide as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Thrombosis Research Institute

Curated by ChEMBL
LigandPNGBDBM50070596(N-Methyl-N-{3-[2-(pyridin-4-ylamino)-ethoxy]-pheny...)
Affinity DataKi:  70nMpH: 7.5Assay Description:Tested for the Inhibition of the catalytic activity of human Thrombin at 25 degree C and pH 7.5.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2012
Entry Details Article

TargetSerine protease 1(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50070596(N-Methyl-N-{3-[2-(pyridin-4-ylamino)-ethoxy]-pheny...)
Affinity DataKi: >5.00E+5nMpH: 7.5Assay Description:Tested for the Inhibition of the catalytic activity of bovine trypsin at 25 degree C and pH 7.5.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2012
Entry Details Article

TargetPlasminogen(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50070596(N-Methyl-N-{3-[2-(pyridin-4-ylamino)-ethoxy]-pheny...)
Affinity DataKi: >5.00E+5nMpH: 7.5Assay Description:Tested for the Inhibition of the catalytic activity of human plasmin at 25 degree C and pH 7.5.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2012
Entry Details Article